Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2(A) Receptor to Promote the Establishment of Infection

Adenosine is an endogenously released purine nucleoside that signals through four widely expressed G protein-coupled receptors: A1, A2(A), A2(B), and A3. Of these, A(2A)R is recognized as mediating major adenosine anti-inflammatory activity. During cutaneous leishmaniasis, adenosine induces immunosu...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Lima, Mikhael H. F., Sacramento, Lais A., Quirino, Gustavo F. S., Ferreira, Marcela D., Benevides, Luciana, Santana, Alynne K. M., Cunha, Fernando Q., Almeida, Roque P., Silva, João S., Carregaro, Vanessa
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517451/
https://ncbi.nlm.nih.gov/pubmed/28775724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00815
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