Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2(A) Receptor to Promote the Establishment of Infection

Adenosine is an endogenously released purine nucleoside that signals through four widely expressed G protein-coupled receptors: A1, A2(A), A2(B), and A3. Of these, A(2A)R is recognized as mediating major adenosine anti-inflammatory activity. During cutaneous leishmaniasis, adenosine induces immunosu...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Lima, Mikhael H. F., Sacramento, Lais A., Quirino, Gustavo F. S., Ferreira, Marcela D., Benevides, Luciana, Santana, Alynne K. M., Cunha, Fernando Q., Almeida, Roque P., Silva, João S., Carregaro, Vanessa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517451/
https://ncbi.nlm.nih.gov/pubmed/28775724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00815
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