Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2(A) Receptor to Promote the Establishment of Infection

Adenosine is an endogenously released purine nucleoside that signals through four widely expressed G protein-coupled receptors: A1, A2(A), A2(B), and A3. Of these, A(2A)R is recognized as mediating major adenosine anti-inflammatory activity. During cutaneous leishmaniasis, adenosine induces immunosu...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Lima, Mikhael H. F., Sacramento, Lais A., Quirino, Gustavo F. S., Ferreira, Marcela D., Benevides, Luciana, Santana, Alynne K. M., Cunha, Fernando Q., Almeida, Roque P., Silva, João S., Carregaro, Vanessa
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517451/
https://ncbi.nlm.nih.gov/pubmed/28775724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00815
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