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Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor.

In most instances, fusion of differentiated cell types with fibroblasts has resulted in the extinction of differentiation-specific traits of the nonfibroblast parental cell. To explore the genetic basis of this phenomenon, we have used a series of somatic cell hybrids between myeloma cells and fibro...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Bergman, Y, Strich, B, Sharir, H, Ber, R, Laskov, R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2107075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08182.x
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