Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor.

In most instances, fusion of differentiated cell types with fibroblasts has resulted in the extinction of differentiation-specific traits of the nonfibroblast parental cell. To explore the genetic basis of this phenomenon, we have used a series of somatic cell hybrids between myeloma cells and fibro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Bergman, Y, Strich, B, Sharir, H, Ber, R, Laskov, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1990
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2107075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08182.x
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