Core shell lipid-polymer hybrid nanoparticles with combined docetaxel and molecular targeted therapy for the treatment of metastatic prostate cancer

Many prostate cancers relapse after initial chemotherapy treatment. Combining molecular and chemotherapy together with encapsulation of drugs in nanocarriers provides effective drug delivery and toxicity reduction. We developed core shell lipid-polymer hybrid nanoparticles (CSLPHNPs) with poly (lact...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Qi, Alshaker, Heba, Böhler, Torsten, Srivats, Shyam, Chao, Yimin, Cooper, Colin, Pchejetski, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517417/
https://ncbi.nlm.nih.gov/pubmed/28724986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06142-x
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