Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

A cosmid clone containing closely linked beta-lactam antibiotic biosynthetic genes was isolated from a gene library of Flavobacterium sp. SC 12,154. The location within the cluster of the DNA thought to contain the gene for delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (ACVS), the firs...

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Detalhes bibliográficos
Main Authors: Smith, D J, Burnham, M K, Bull, J H, Hodgson, J E, Ward, J M, Browne, P, Brown, J, Barton, B, Earl, A J, Turner, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551730/
https://ncbi.nlm.nih.gov/pubmed/2107074
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