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Optimising use of thiopurines in inflammatory bowel disease

Azathioprine (AZA) and 6-mercaptopurine (6-MP) are the most widely used immunosuppressive therapies in inflammatory bowel disease. Pretreatment measurement of thiopurine methyltransferase (TPMT) activity is recommended and although conventional practice is to use a dose of 2 mg/kg AZA (1 mg/kg 6-MP)...

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Publicado en:Frontline Gastroenterol
Autores principales: Raj, Lawrence Sunder, Hawthorne, A Barney
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517153/
https://ncbi.nlm.nih.gov/pubmed/28839543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/fg.2009.000174
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