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New library construction method for single-cell genomes

A central challenge in sequencing single-cell genomes is the accurate determination of point mutations, phasing of these mutations, and identifying copy number variations with few assumptions. Ideally, this is accomplished under as low sequencing coverage as possible. Here we report our attempt to m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xi, Larry, Belyaev, Alexander, Spurgeon, Sandra, Wang, Xiaohui, Gong, Haibiao, Aboukhalil, Robert, Fekete, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517011/
https://ncbi.nlm.nih.gov/pubmed/28723968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181163
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