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Evidence for prehistoric origins of the G2019S mutation in the North African Berber population

The most common cause of the monogenic form of Parkinson’s disease known so far is the G2019S mutation of the leucine-rich repeat kinase 2 (LRRK2) gene. Its frequency varies greatly among ethnic groups and geographic regions ranging from less than 0.1% in Asia to 40% in North Africa. This mutation h...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Ben El Haj, Rafiqua, Salmi, Ayyoub, Regragui, Wafa, Moussa, Ahmed, Bouslam, Naima, Tibar, Houyam, Benomar, Ali, Yahyaoui, Mohamed, Bouhouche, Ahmed
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517005/
https://ncbi.nlm.nih.gov/pubmed/28723952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181335
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