Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice

We previously showed that activation of G protein-coupled receptor 40/free fatty acid receptor 1 (GPR40/FFAR1) signaling modulates descending inhibition of pain. In this study, we investigated the involvement of fatty acid-GPR40/FFAR1 signaling in the transition from acute to chronic pain. We used G...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakamoto, Kazuo, Aizawa, Fuka, Miyagi, Kei, Yamashita, Takuya, Mankura, Mitsumasa, Koyama, Yutaka, Kasuya, Fumiyo, Hirasawa, Akira, Kurihara, Takashi, Miyata, Atsuro, Tokuyama, Shogo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516985/
https://ncbi.nlm.nih.gov/pubmed/28723961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180610
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