Oscillation dynamics underlie functional switching of NF-κB for B-cell activation

Transcription factor nuclear factor kappa B (NF-κB) shows cooperative switch-like activation followed by prolonged oscillatory nuclear translocation in response to extracellular stimuli. These dynamics are important for activation of the NF-κB transcriptional machinery, however, NF-κB activity regul...

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Vydáno v:NPJ Syst Biol Appl
Hlavní autoři: Inoue, Kentaro, Shinohara, Hisaaki, Behar, Marcelo, Yumoto, Noriko, Tanaka, Gouhei, Hoffmann, Alexander, Aihara, Kazuyuki, Okada-Hatakeyama, Mariko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516862/
https://ncbi.nlm.nih.gov/pubmed/28725478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjsba.2016.24
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