The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

We have analyzed t(1;14)(p32;q11) chromosome translocations from two patients with T cell acute lymphocytic leukemia. The chromosome 1 breakpoints of these patients lie within a kilobasepair of each other, and thus define a genetic locus (designated tal) involved in T cell oncogenesis. Moreover, we...

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Bibliographic Details
Main Authors: Chen, Q, Cheng, J T, Tasi, L H, Schneider, N, Buchanan, G, Carroll, A, Crist, W, Ozanne, B, Siciliano, M J, Baer, R
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC551682/
https://ncbi.nlm.nih.gov/pubmed/2303035
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