Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

BACKGROUND: Regulation of gene expression by microRNAs (miRNAs) is critical for determining cellular fate and function. Dysregulation of miRNA expression contributes to the development and progression of multiple diseases. miRNA can target multiple mRNAs, making deconvolution of the effects of miRNA...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Moss, Tyler J, Luo, Zijun, Seviour, Elena G, Sehgal, Vasudha, Lu, Yiling, Hill, Steven M, Rupaimoole, Rajesha, Lee, Ju-Seog, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K, Azencott, Robert, Gray, Joe W, Mukherjee, Sach, Mills, Gordon B, Ram, Prahlad T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516802/
https://ncbi.nlm.nih.gov/pubmed/28725457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjsba.2015.1
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