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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

The myc oncogene is overexpressed in almost half of all breast and ovarian cancers, but attempts at therapeutic interventions against myc have proven to be challenging. Myc regulates multiple biological processes, including the cell cycle, and as such is associated with cell proliferation and tumor...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Seviour, E G, Sehgal, V, Lu, Y, Luo, Z, Moss, T, Zhang, F, Hill, S M, Liu, W, Maiti, S N, Cooper, L, Azencot, R, Lopez-Berestein, G, Rodriguez-Aguayo, C, Roopaimoole, R, Pecot, C, Sood, A K, Mukherjee, S, Gray, J W, Mills, G B, Ram, P T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522411/
https://ncbi.nlm.nih.gov/pubmed/25639871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.469
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