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Discrete domains of human U6 snRNA required for the assembly of U4/U6 snRNP and splicing complexes.

U6 snRNA sequences required for assembly of U4/U6 snRNP and splicing complexes were determined by in vitro reconstitution of snRNPs. Both mutagenesis and chemical modification/interference assays identify a U6 snRNA domain required for U4/U6 snRNP formation. The results support the existence of a U4...

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Main Authors: Bindereif, A, Wolff, T, Green, M R
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC551655/
https://ncbi.nlm.nih.gov/pubmed/2136831
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