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Discrete domains of human U6 snRNA required for the assembly of U4/U6 snRNP and splicing complexes.

U6 snRNA sequences required for assembly of U4/U6 snRNP and splicing complexes were determined by in vitro reconstitution of snRNPs. Both mutagenesis and chemical modification/interference assays identify a U6 snRNA domain required for U4/U6 snRNP formation. The results support the existence of a U4...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Bindereif, A, Wolff, T, Green, M R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1990
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2136831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08102.x
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