(−)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata, Induces DNA Double-Strand Breaks

Twelve benzylisoquinoline alkaloids, including pavine and phenanthroindolizidine types, were isolated from a MeOH/CH(2)Cl(2) extract of Cryptocarya laevigata (stem bark) through bioactivity-guided fractionation for antitumor effects. Selected compounds were evaluated for antiproliferative activity a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Nat Prod
Main Authors: Suzuki, Yuki, Saito, Yohei, Goto, Masuo, Newman, David J., O’Keefe, Barry R., Lee, Kuo-Hsiung, Nakagawa-Goto, Kyoko
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516478/
https://ncbi.nlm.nih.gov/pubmed/28099003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b01153
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki