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Cardiac electrophysiologic and antiarrhythmic actions of a pavine alkaloid derivative, O-methyl-neocaryachine, in rat heart

1. O-methyl-neocaryachine (OMNC) suppressed the ischaemia/reperfusion-induced ventricular arrhythmias in Langendorff-perfused rat hearts (EC(50)=4.3 μM). Its electrophysiological effects on cardiac myocytes and the conduction system in isolated hearts as well as the electromechanical effects on the...

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Detalhes bibliográficos
Main Authors: Chang, Gwo-Jyh, Su, Ming-Jai, Hung, Li-Man, Lee, Shoei-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573366/
https://ncbi.nlm.nih.gov/pubmed/12023949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704736
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