Electrophysiological basis for the antiarrhythmic action and positive inotropy of HA-7, a furoquinoline alkaloid derivative, in rat heart

1. HA-7, a new synthetic derivative of furoquinoline alkaloid, increased the contractile force of right ventricular strips and effectively suppressed the ischaemia-reperfusion induced polymorphic ventricular tachyrhythmias in adult rat heart (EC(50)=2.8 μM). 2. In rat ventricular myocytes, HA-7 conc...

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Bibliographic Details
Main Authors: Su, Ming-Jai, Chang, Gwo-Jyh, Wu, Mei-Hwan, Kuo, Sheng-Chu
Format: Artigo
Language:Inglês
Published: 1997
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565072/
https://ncbi.nlm.nih.gov/pubmed/9421274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701510
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