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Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells
OBJECTIVE: Determine mechanisms responsible for enhanced statin efficacy in a novel statin combination we name STOX (STatin–OXysterol). METHODS: Ovarian cancer cell lines were treated with combinations of statins and oxysterols. Cell viability was determined by a modified MTT assay. Apoptosis was ev...
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| Publicat a: | Gynecol Oncol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5516475/ https://ncbi.nlm.nih.gov/pubmed/25134999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2014.08.015 |
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