Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome.

Translocations involving chromosome 11, band q23, are frequent recurring abnormalities in human acute lymphoblastic and acute myeloid leukemia. We used 19 biotin-labeled probes derived from genes and anonymous cosmids for hybridization to metaphase chromosomes from leukemia cells that contained four...

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Main Authors: Rowley, J D, Diaz, M O, Espinosa, R, Patel, Y D, van Melle, E, Ziemin, S, Taillon-Miller, P, Lichter, P, Evans, G A, Kersey, J H
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55164/
https://ncbi.nlm.nih.gov/pubmed/2251277
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