The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.

Chromosomal region 11q23 is frequently rearranged in acute lymphocytic leukemias (ALLs) and in acute myeloid leukemias (AMLs), mostly in reciprocal exchanges with various translocation partners. The most common of these translocations is t(4;11)(q21;q23). It is present in approximately 10% of ALL pa...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gu, Y, Cimino, G, Alder, H, Nakamura, T, Prasad, R, Canaani, O, Moir, D T, Jones, C, Nowell, P C, Croce, C M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.21.10464
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