The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.

Chromosomal region 11q23 is frequently rearranged in acute lymphocytic leukemias (ALLs) and in acute myeloid leukemias (AMLs), mostly in reciprocal exchanges with various translocation partners. The most common of these translocations is t(4;11)(q21;q23). It is present in approximately 10% of ALL pa...

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Hlavní autoři: Gu, Y, Cimino, G, Alder, H, Nakamura, T, Prasad, R, Canaani, O, Moir, D T, Jones, C, Nowell, P C, Croce, C M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC50359/
https://ncbi.nlm.nih.gov/pubmed/1438235
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