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Opinion: hazards faced by macromolecules when confined to thin aqueous films
Samples prepared for single-particle electron cryo-microscopy (cryo-EM) necessarily have a very high surface-to-volume ratio during the short period of time between thinning and vitrification. During this time, there is an obvious risk that macromolecules of interest may adsorb to the air–water inte...
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| Published in: | Biophys Rep |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Berlin Heidelberg
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5516009/ https://ncbi.nlm.nih.gov/pubmed/28781996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s41048-016-0026-3 |
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