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Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy

The constant increase in cardiovascular disease rate coupled with significant drawbacks of existing therapies emphasise the necessity to improve therapeutic strategies. Natural flavonoids exert innumerable pharmacological effects in humans. Here, we demonstrate the effects of chrysin, a natural flav...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ravishankar, Divyashree, Salamah, Maryam, Attina, Alda, Pothi, Radhika, Vallance, Thomas M., Javed, Muhammad, Williams, Harry F., Alzahrani, Eman M. S., Kabova, Elena, Vaiyapuri, Rajendran, Shankland, Kenneth, Gibbins, Jonathan, Strohfeldt, Katja, Greco, Francesca, Osborn, Helen M. I., Vaiyapuri, Sakthivel
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515887/
https://ncbi.nlm.nih.gov/pubmed/28720875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05936-3
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