Platelet expression of PKCepsilon oncoprotein in myelofibrosis is associated with disease severity and thrombotic risk

BACKGROUND: Myelofibrosis (MF) is the most aggressive Philadelphia-negative chronic myeloproliferative neoplasm (MPN) with high morbidity and mortality due to thrombo-hemorrhagic complications and leukemic transformation. MF is characterized by profound alterations of megakaryocytopoiesis, with cons...

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Publicat a:Ann Transl Med
Autors principals: Masselli, Elena, Carubbi, Cecilia, Pozzi, Giulia, Martini, Silvia, Aversa, Franco, Galli, Daniela, Gobbi, Giuliana, Mirandola, Prisco, Vitale, Marco
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515809/
https://ncbi.nlm.nih.gov/pubmed/28758099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.06.22
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