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Loss of WDFY3 Ameliorates Severity of Serum Transfer-Induced Arthritis Independently of Autophagy

WDFY3 is a master regulator of selective autophagy that we recently showed to interact with TRAF6 and augment RANKL-induced osteoclastogenesis in vitro and in vivo via the NF-κB pathway. Since the NF-κB pathway plays a major role in inflammation herein, we investigate the role of WDFY3 in an arthrit...

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Foilsithe in:Cell Immunol
Main Authors: Wu, Dennis J., Adamopoulos, Iannis E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515728/
https://ncbi.nlm.nih.gov/pubmed/28449847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.04.001
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