Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis

Recently, autophagy-related proteins were shown to regulate osteoclast mediated bone resorption, a critical process in autoimmune diseases such as rheumatoid arthritis. However, the role of autophagy-linked FYVE containing protein, WDFY3, in osteoclast biology remains elusive. WDFY3 is a master regu...

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Bibliographic Details
Published in:J Autoimmun
Main Authors: Wu, Dennis J., Gu, Ran, Sarin, Ritu, Zavodovskaya, Regina, Chen, Chia-Pei, Christiansen, Blaine A., Adamopoulos, Iannis E.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003737/
https://ncbi.nlm.nih.gov/pubmed/27330028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.06.004
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