Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model

BACKGROUND: Studies combining immune checkpoint inhibitors with external beam radiation have shown a therapeutic advantage over each modality alone. The purpose of these works is to evaluate the potential of targeted delivery of high LET radiation to the tumor microenvironment via an immune checkpoi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EJNMMI Res
Egile Nagusiak: Nedrow, Jessie R., Josefsson, Anders, Park, Sunju, Bäck, Tom, Hobbs, Robert F., Brayton, Cory, Bruchertseifer, Frank, Morgenstern, Alfred, Sgouros, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2017
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515722/
https://ncbi.nlm.nih.gov/pubmed/28721684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0303-2
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