Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model

BACKGROUND: Studies combining immune checkpoint inhibitors with external beam radiation have shown a therapeutic advantage over each modality alone. The purpose of these works is to evaluate the potential of targeted delivery of high LET radiation to the tumor microenvironment via an immune checkpoi...

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Detaylı Bibliyografya
Yayımlandı:EJNMMI Res
Asıl Yazarlar: Nedrow, Jessie R., Josefsson, Anders, Park, Sunju, Bäck, Tom, Hobbs, Robert F., Brayton, Cory, Bruchertseifer, Frank, Morgenstern, Alfred, Sgouros, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2017
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515722/
https://ncbi.nlm.nih.gov/pubmed/28721684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0303-2
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