MicroRNA-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats By Upregulating Mitochondrial Translation

BACKGROUND: Excessive reactive oxygen species generated in mitochondria has been implicated as a causal event in hypertensive cardiomyopathy. Multiple recent studies suggest that microRNAs (miRNAs) are able to translocate to mitochondria to modulate mitochondrial activities, but the medical signific...

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Udgivet i:Circulation
Main Authors: Li, Huaping, Zhang, Xiaorong, Wang, Feng, Zhou, Ling, Yin, Zhongwei, Fan, Jiahui, Nie, Xiang, Wang, Peihua, Fu, Xiang-Dong, Chen, Chen, Wang, Dao Wen
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515592/
https://ncbi.nlm.nih.gov/pubmed/27542393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.023926
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