Recombinant Adeno-Associated Virus-Mediated Delivery of MicroRNA-21-3p Lowers Hypertension

Hypertension is the most important risk factor for cardiovascular diseases worldwide. However, the underlying molecular mechanisms of hypertension are complex and remain largely elusive. Here, we described a novel, microRNA-dependent therapeutic strategy for hypertension. First, we found that plasma...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Feng Wang, Qin Fang, Chen Chen, Ling Zhou, Huaping Li, Zhongwei Yin, Yan Wang, Chun Xia Zhao, Xiao Xiao, Dao Wen Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018-06-01
Colecção:Molecular Therapy: Nucleic Acids
Assuntos:
rAAV
miR-21-3p
hypertension
ADRA2B
VSMC
vascular remodeling
α-SMA
OPN
NF-κB
SRF
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2162253117302913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados