RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes

Increasing evidence suggests that diverse RNA binding proteins (RBPs) interact with regulatory RNAs to regulate transcription. RBFox2 is a well-characterized pre-mRNA splicing regulator, but we now encounter an unexpected paradigm where depletion of this RBP induces widespread increase in nascent RN...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Wei, Chaoliang, Xiao, Rui, Chen, Liang, Cui, Hanwei, Zhou, Yu, Xue, Yuanchao, Hu, Jing, Zhou, Bing, Tsutsui, Taiki, Qiu, Jinsong, Li, Hairi, Tang, Liling, Fu, Xiang-Dong
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515591/
https://ncbi.nlm.nih.gov/pubmed/27211866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.013
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