Botulinum Neurotoxin Serotype A Suppresses Neurotransmitter Release from Afferent as Well as Efferent Nerves in the Urinary Bladder

BACKGROUND: Botulinum neurotoxin A (BoNTA), which alleviates overactive bladder symptoms, is thought to act predominantly via the inhibition of transmitter release from parasympathetic nerves. However, actions at other sites such as afferent nerve terminals are possible. OBJECTIVE: To evaluate the e...

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Detalhes bibliográficos
Publicado no:Eur Urol
Main Authors: Ikeda, Youko, Zabbarova, Irina V., Birder, Lori A., de Groat, William C., McCarthy, Carly J., Hanna-Mitchell, Ann T., Kanai, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515465/
https://ncbi.nlm.nih.gov/pubmed/22480459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.03.031
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