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Predicting the protein half-life in tissue from its cellular properties

Protein half-life is an important feature of protein homeostasis (proteostasis). The increasing number of in vivo and in vitro studies using high throughput proteomics provide estimates of the protein half-lives in tissues and cells. However, protein half-lives in cells and tissues are different. Du...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Rahman, Mahbubur, Sadygov, Rovshan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515413/
https://ncbi.nlm.nih.gov/pubmed/28719664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180428
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