Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth

BACKGROUND: We sought to address whether CF macrophages have a primary functional defect as a consequence of CFTR loss and thus contribute to the onset of infection and inflammation observed in CF lung disease. METHODS: Monocyte derived macrophages (MDMs) were prepared from newborn CF and non-CF pig...

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Опубликовано в: :J Cyst Fibros
Главные авторы: Paemka, Lily, McCullagh, Brian N., Abou Alaiwa, Mahmoud H., Stoltz, David A., Dong, Qian, Randak, Christoph O., Gray, Robert D., McCray, Paul B.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515361/
https://ncbi.nlm.nih.gov/pubmed/28377087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2017.03.007
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