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Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival

Increasing antibiotic resistance and the declining rate at which new antibiotics come into use create a need to increase the efficacy of existing antibiotics. The aminoglycoside tobramycin is standard-of-care for many types of Pseudomonas aeruginosa infections, including those in the lungs of cystic...

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Detalles Bibliográficos
Publicado en:NPJ Biofilms Microbiomes
Main Authors: Kaushik, Karishma S, Stolhandske, Jake, Shindell, Orrin, Smyth, Hugh D, Gordon, Vernita D
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515257/
https://ncbi.nlm.nih.gov/pubmed/28721244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbiofilms.2016.6
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