A search for synergy in the binding kinetics of Trastuzumab and Pertuzumab whole and F(ab) to Her2

Therapeutic efficacy resulting from combining Trastuzumab and Pertuzumab in the treatment of Her2 overexpressing breast cancer patients has been shown to increase patient survival. This is thought to arise from inhibition of receptor dimerization and the immune tagging of the cancer cells; however,...

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Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Main Authors: Lua, Wai-Heng, Gan, Samuel Ken-En, Lane, David Philip, Verma, Chandra Shekhar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515203/
https://ncbi.nlm.nih.gov/pubmed/28721368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbcancer.2015.12
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