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Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders

Cysteinyl leukotrienes (cysLTs), LTC4, and its extracellular metabolites, LTD4 and LTE4, have varied and multiple roles in mediating eosinophilic disorders including host defense against parasitic helminthes and allergic inflammation, especially in the lung and in asthma. CysLTs are known to act thr...

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Détails bibliographiques
Publié dans:Front Med (Lausanne)
Auteurs principaux: Thompson-Souza, Glaucia A., Gropillo, Isabella, Neves, Josiane S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515036/
https://ncbi.nlm.nih.gov/pubmed/28770202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2017.00106
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