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Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids

The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood. We use a proteotoxicity model based upon the inducibl...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Currais, Antonio, Quehenberger, Oswald, M Armando, Aaron, Daugherty, Daniel, Maher, Pam, Schubert, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514994/
https://ncbi.nlm.nih.gov/pubmed/28721267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjamd.2016.12
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