Human Splicing Factor SF3a, but Not SF1, Is Essential for Pre-mRNA Splicing In Vivo
The three subunits of human splicing factor SF3a are essential for the formation of the functional 17S U2 snRNP and prespliceosome assembly in vitro. RNAi-mediated depletion indicates that each subunit is essential for viability of human cells. Knockdown of single subunits results in a general block...
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| Опубликовано в:: | Mol Biol Cell |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Cell Biology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15647371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-11-1034 |
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