Chargement en cours...

Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency

Enforced ectopic expression of a cocktail of pluripotency-associated genes such as Oct4, Sox2, Klf4 and c-Myc can reprogram somatic cells into induced pluripotent stem cells (iPSCs). The remarkable proliferation ability of iPSCs and their aptitude to redifferentiate into any cell lineage makes these...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Epigenomics
Auteurs principaux: van den Hurk, Mark, Kenis, Gunter, Bardy, Cedric, van den Hove, Daniel L, Gage, Fred H, Steinbusch, Harry W, Rutten, Bart P
Format: Artigo
Langue:Inglês
Publié: Future Medicine Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514980/
https://ncbi.nlm.nih.gov/pubmed/27419933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2016-0032
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!