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Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency
Enforced ectopic expression of a cocktail of pluripotency-associated genes such as Oct4, Sox2, Klf4 and c-Myc can reprogram somatic cells into induced pluripotent stem cells (iPSCs). The remarkable proliferation ability of iPSCs and their aptitude to redifferentiate into any cell lineage makes these...
Kaydedildi:
| Yayımlandı: | Epigenomics |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Future Medicine Ltd
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514980/ https://ncbi.nlm.nih.gov/pubmed/27419933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2016-0032 |
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