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Aurora Kinase Inhibitor ZM447439 Blocks Chromosome-induced Spindle Assembly, the Completion of Chromosome Condensation, and the Establishment of the Spindle Integrity Checkpoint in Xenopus Egg Extracts

The Aurora family kinases contribute to accurate progression through several mitotic events. ZM447439 (“ZM”), the first Aurora family kinase inhibitor to be developed and characterized, was previously found to interfere with the mitotic spindle integrity checkpoint and chromosome segregation. Here,...

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Detaylı Bibliyografya
Asıl Yazarlar: Gadea, Bedrick B., Ruderman, Joan V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC551494/
https://ncbi.nlm.nih.gov/pubmed/15616188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0891
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