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A Plasma Membrane Pool of Phosphatidylinositol 4-Phosphate Is Generated by Phosphatidylinositol 4-Kinase Type-III Alpha: Studies with the PH Domains of the Oxysterol Binding Protein and FAPP1

The PH domains of OSBP and FAPP1 fused to GFP were used to monitor PI(4)P distribution in COS-7 cells during manipulations of PI 4-kinase (PI4K) activities. Both domains were associated with the Golgi and small cytoplasmic vesicles, and a small fraction of OSBP-PH was found at the plasma membrane (P...

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Main Authors: Balla, Andras, Tuymetova, Galina, Tsiomenko, Arnold, Várnai, Péter, Balla, Tamas
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC551492/
https://ncbi.nlm.nih.gov/pubmed/15635101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0578
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