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Synthesis and evaluation of anthranilamide-based derivatives as FXa inhibitors
Factor Xa (FXa) plays a significant role in the blood coagulation cascade and is a promising target for anticoagulation drugs. Three oral FXa inhibitors have been approved by FDA for treating thrombotic diseases. In this study, 43 novel compounds were synthesized anthranilamide-based FXa inhibitors...
Sparad:
| I publikationen: | Oncotarget |
|---|---|
| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Impact Journals LLC
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514901/ https://ncbi.nlm.nih.gov/pubmed/28415603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16427 |
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