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Reconstruction from limited single-particle diffraction data via simultaneous determination of state, orientation, intensity, and phase

Free-electron lasers now have the ability to collect X-ray diffraction patterns from individual molecules; however, each sample is delivered at unknown orientation and may be in one of several conformational states, each with a different molecular structure. Hit rates are often low, typically around...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Donatelli, Jeffrey J., Sethian, James A., Zwart, Peter H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514772/
https://ncbi.nlm.nih.gov/pubmed/28652365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708217114
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