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CIDE domains form functionally important higher-order assemblies for DNA fragmentation

Cell death-inducing DFF45-like effector (CIDE) domains, initially identified in apoptotic nucleases, form a family with diverse functions ranging from cell death to lipid homeostasis. Here we show that the CIDE domains of Drosophila and human apoptotic nucleases Drep2, Drep4, and DFF40 all form head...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Choi, Jae Young, Qiao, Qi, Hong, Se-Hoon, Kim, Chang Min, Jeong, Jae-Hee, Kim, Yeon-Gil, Jung, Yong-Keun, Wu, Hao, Park, Hyun Ho
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514754/
https://ncbi.nlm.nih.gov/pubmed/28652364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705949114
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