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CIDE domains form functionally important higher-order assemblies for DNA fragmentation
Cell death-inducing DFF45-like effector (CIDE) domains, initially identified in apoptotic nucleases, form a family with diverse functions ranging from cell death to lipid homeostasis. Here we show that the CIDE domains of Drosophila and human apoptotic nucleases Drep2, Drep4, and DFF40 all form head...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514754/ https://ncbi.nlm.nih.gov/pubmed/28652364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705949114 |
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