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Ablation of PRC1 by Small Interfering RNA Demonstrates that Cytokinetic Abscission Requires a Central Spindle Bundle in Mammalian Cells, whereas Completion of Furrowing Does Not

The temporal and spatial regulation of cytokinesis requires an interaction between the anaphase mitotic spindle and the cell cortex. However, the relative roles of the spindle asters or the central spindle bundle are not clear in mammalian cells. The central spindle normally serves as a platform to...

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Main Authors: Mollinari, Cristiana, Kleman, Jean-Philippe, Saoudi, Yasmina, Jablonski, Sandra A., Perard, Julien, Yen, Tim J., Margolis, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC551472/
https://ncbi.nlm.nih.gov/pubmed/15616196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0346
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