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PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone

Midzone microtubules of mammalian cells play an essential role in the induction of cell cleavage, serving as a platform for a number of proteins that play a part in cytokinesis. We demonstrate that PRC1, a mitotic spindle-associated Cdk substrate that is essential to cell cleavage, is a microtubule...

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Detalhes bibliográficos
Main Authors: Mollinari, Cristiana, Kleman, Jean-Philippe, Jiang, Wei, Schoehn, Guy, Hunter, Tony, Margolis, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173564/
https://ncbi.nlm.nih.gov/pubmed/12082078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200111052
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